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Fetal Aneuploidy Screening Mastery

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Single Umbilical Artery (SUA)

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Learn to identify the number of vessels in the umbilical cord. This session covers the clinical implications of a single umbilical artery (SUA), including its impact on fetal growth monitoring and the need for a detailed cardiac evaluation.

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Complete this lesson and pass the quiz to earn 10 Karma Points and move one step closer to your Fetal Aneuploidy Screening Mastery Certification.

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1. How many vessels does a normal umbilical cord contain, and what are they?
Two vessels — one artery and one vein Three vessels — two arteries and one vein Three vessels — one artery and two veins Four vessels — two arteries and two veins
2. Single Umbilical Artery (SUA) holds which distinction in terms of its prevalence among human malformations?
It is the rarest pathological cord condition It is one of the most frequent malformations in humans It is the second most common cord anomaly after cord cysts It occurs exclusively in multiple gestations
3. Which transducer view and imaging modality is highlighted as the most effective method for diagnosing SUA prenatally?
Longitudinal cord view with B-mode only Transverse pelvic view around the fetal bladder using color or power Doppler Axial abdominal view with spectral Doppler Coronal fetal view with M-mode imaging
4. Approximately what proportion of fetuses with SUA have an associated chromosomal abnormality?
5% 10% 17% 30%
5. Which chromosomal aneuploidy is most commonly associated with Single Umbilical Artery?
Trisomy 21 Trisomy 13 Trisomy 18 Monosomy X
6. Beyond Trisomy 18, which three other karyotypic abnormalities are specifically linked to SUA?
Trisomy 21, Trisomy 13, and Monosomy X Trisomy 13, Turner syndrome (45,X), and Triploidy Trisomy 21, Triploidy, and Monosomy X Trisomy 13, Trisomy 21, and Tetrasomy 12p
7. The prevalence of structural fetal abnormalities associated with SUA spans a wide reported range. What does the upper end of this range reach?
Over 20% Over 30% Over 47% Over 60%
8. What is the mandatory next step in management once Single Umbilical Artery is identified sonographically?
Immediate amniocentesis Referral for fetal echocardiography only A comprehensive prenatal anatomic survey to exclude additional anomalies Repeat ultrasound at 32 weeks only
9. In a genuinely low-risk patient where SUA appears to be an isolated finding with no additional anomalies detected, is immediate invasive chromosomal investigation routinely warranted?
Yes — SUA always mandates karyotyping regardless of risk profile No, isolated SUA in a low-risk patient may not warrant chromosomal investigation Only if maternal age exceeds 35 years Only if SUA is left-sided
10. Even after a normal prenatal workup in an SUA pregnancy, what important information must parents be counselled about?
SUA always resolves postnatally and no follow-up is needed Minor defects only become detectable at birth despite a normal antenatal workup A repeat third-trimester scan is contraindicated Delivery must occur in a tertiary center regardless of other findings