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Fetal Aneuploidy Screening Mastery

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The Nasal Bone (NB) Assessment

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Learn the secrets of early nasal bone assessment. This session covers the precise ultrasound techniques required to visualize the nasal bone between weeks 11 and 13+6, emphasizing how to recognize absence or hypoplasia as significant markers for Trisomy 21.

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Complete this lesson and pass the quiz to earn 10 Karma Points and move one step closer to your Fetal Aneuploidy Screening Mastery Certification.

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1. What is the correct gestational age window for first trimester nasal bone assessment?
10 to 12 weeks 11 to 13 weeks and 6 days 12 to 14 weeks 10 to 11 weeks and 6 days
2. What magnification standard must be met before assessing the nasal bone in the first trimester?
The entire fetal body must fill the screen The fetal head alone must fill the screen The fetal head and thorax must occupy the entire image No specific magnification is required
3. Which two anterior structures must be visible to confirm a correct mid-sagittal face view for nasal bone assessment?
The orbits and upper lip The echogenic tip of the nose and the rectangular shape of the palate The maxilla and mandible The nasal tip and the tongue
4. Which central structure, visible in the mid-sagittal plane, confirms correct fetal positioning for nasal bone assessment?
The cerebellum The cavum septi pellucidi The translucent diencephalon The choroid plexus
5. Which posterior structure completes the four-landmark checklist for an adequate mid-sagittal face view?
The occipital bone The cerebellar vermis The nuchal membrane The posterior fossa cistern
6. How should the transducer be held relative to the nasal bone, and what movement is used to optimise visualisation?
Perpendicular to the nose, with rotational movement Parallel to the nose, with a gentle side-to-side tilt At 45 degrees to the nose, with sliding movement Parallel to the nose, with downward pressure
7. What is the essential echogenicity rule for confirming a visible nasal bone on first trimester ultrasound?
The nasal bone must be less echogenic than the overlying skin The nasal bone and skin should appear equally echogenic The nasal bone must be more echogenic than the overlying skin The nasal bone should appear anechoic relative to the skin
8. The "three distinct lines" sign for nasal bone identification consists of which three structures, from superficial to deep?
Skin, nasal cartilage, nasal bone Skin line, nasal bone line (thicker and more echogenic), and the tip of the nose Nasal bone, skin, and diencephalon Skin, nasal tip, and palate
9. Which classification category applies when the nasal bone line is visualised but appears thin and LESS echogenic than the overlying skin?
Visible — normal finding Less echogenic / unossified Invisible / absent Hypoplastic — requires measurement
10. Which rare facial malformation describes a tube-like appendage that replaces the normal nasal structure, and with which severe facial anomaly is it associated?
Arrhinia — associated with cyclopia Proboscis — associated with cyclopia or synophthalmia Single naris — associated with holoprosencephaly Nasal aplasia — associated with Trisomy 21