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Fetal Aneuploidy Screening Mastery

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The Nuchal Translucency (NT) Scan

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This module focuses on the Nuchal Translucency (NT) scan, a primary first-trimester marker for chromosomal abnormalities. Students will learn the standardized imaging planes and technical requirements for measuring the fluid-filled space at the back of the fetal neck, providing a critical baseline for trisomy risk assessment.

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1. What anatomical structure does Nuchal Translucency (NT) represent?
Fluid in the fetal spine The subcutaneous fluid space at the back of the fetal neck The fetal skin thickness The amnion thickness
2. Between which gestational ages is NT measurement reliably performed?
10–12 weeks 11–14 weeks 12–16 weeks 9–11 weeks
3. What is the minimum CRL required before NT measurement is considered valid?
35 mm 45 mm 55 mm 60 mm
4. Which view is mandatory for a valid NT measurement?
Coronal view Axial view Mid-sagittal view Transverse cerebellar view
5. On the mid-sagittal view, which structure should NOT be visualized to confirm you are not in an off-sagittal plane?
The fetal nose The fetal spine The fetal ear The fetal palate
6. What fetal head position is required during NT measurement?
Hyperflexed (chin on chest) Hyperextended (chin up) Neutral position Any position is acceptable
7. Why is it critical to distinguish the nuchal membrane from the amnion during NT measurement?
The amnion is thicker and gives a falsely low reading Measuring the amnion instead of the nuchal membrane gives a falsely elevated NT The amnion and nuchal membrane are identical in appearance The distinction is only relevant after 13 weeks
8. When multiple NT measurements are taken in the same scan, which value should be recorded?
The smallest measurement The average of all measurements The largest measurement The first measurement obtained
9. Where should the calipers be placed for a correct NT measurement?
Outer edge to outer edge of the nuchal membrane Inner edge to inner edge of the nuchal membrane Outer edge to inner edge On the skin surface only
10. When interpreting NT, why should a fixed cut-off alone NOT be the sole criterion used?
Fixed cut-offs are banned by FMF guidelines NT increases with CRL, so a fixed cut-off ignores gestational age variation NT is independent of fetal size Fixed cut-offs only apply to twin pregnancies